Susanna Hall
Susanna Hall (née Shakespeare; baptised 26 May 1583 – 11 July 1649) was the oldest child of William Shakespeare and Anne Hathaway, and the older sister of twins Judith Quiney and Hamnet Shakespeare. She married John Hall, a local physician, in 1607. They had one daughter, named Elizabeth, in 1608. Elizabeth married Thomas Nash, son of Anthony Nash on 22 April 1626 at Holy Trinity Church, Stratford-upon-Avon.
Reference：https://en.wikipedia.org/wiki/Susanna_Hall
Hamnet Shakespeare
Hamnet Shakespeare (baptised 2 February 1585 – buried 11 August 1596) was the only son of William Shakespeare and Anne Hathaway, and the fraternal twin of Judith Shakespeare. He died at the age of 11. Some Shakespearean scholars speculate on the relationship between Hamnet and his father's later play Hamlet, as well as on possible connections between Hamnet's death and the writing of King John, Romeo and Juliet, Julius Caesar, and Twelfth Night.
Judith Quiney
Judith Quiney (baptised 2 February 1585 – 9 February 1662), née Shakespeare, was the younger daughter of William Shakespeare and Anne Hathaway and the fraternal twin of their only son Hamnet Shakespeare. She married Thomas Quiney, a vintner of Stratford-upon-Avon. The circumstances of the marriage, including Quiney's misconduct, may have prompted the rewriting of Shakespeare's will. Thomas was struck out, while Judith's inheritance was attached with provisions to safeguard it from her husband. The bulk of Shakespeare's estate was left, in an elaborate fee tail, to his elder daughter Susanna and her male heirs.
Judith and Thomas Quiney had three children. By the time of Judith Quiney's death, she had outlived her children by many years. She has been depicted in several works of fiction as part of an attempt to piece together unknown portions of her father's life.
Reference：https://en.wikipedia.org/wiki/Judith_Quiney